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Glycocalyx Degradation Induces a Proinflammatory Phenotype and Increased Leukocyte Adhesion in Cultured Endothelial Cells under Flow

Leukocyte adhesion to the endothelium is an early step in the pathogenesis of atherosclerosis. Effective adhesion requires the binding of leukocytes to their cognate receptors on the surface of endothelial cells. The glycocalyx covers the surface of endothelial cells and is important in the mechanot...

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Detalles Bibliográficos
Autores principales: McDonald, Karli K., Cooper, Scott, Danielzak, Lisa, Leask, Richard L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5132265/
https://www.ncbi.nlm.nih.gov/pubmed/27907146
http://dx.doi.org/10.1371/journal.pone.0167576