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Action mechanisms of histone deacetylase inhibitors in the treatment of hematological malignancies

Histone deacetylases (HDACs) critically regulate gene expression by determining the acetylation status of histones. Studies have increasingly focused on the activities of HDACs, especially involving non‐histone proteins, and their various biological effects. Aberrant HDAC expression observed in seve...

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Detalles Bibliográficos
Autores principales: Imai, Yoichi, Maru, Yoshiro, Tanaka, Junji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5132279/
https://www.ncbi.nlm.nih.gov/pubmed/27554046
http://dx.doi.org/10.1111/cas.13062