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Action mechanisms of histone deacetylase inhibitors in the treatment of hematological malignancies
Histone deacetylases (HDACs) critically regulate gene expression by determining the acetylation status of histones. Studies have increasingly focused on the activities of HDACs, especially involving non‐histone proteins, and their various biological effects. Aberrant HDAC expression observed in seve...
Autores principales: | Imai, Yoichi, Maru, Yoshiro, Tanaka, Junji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5132279/ https://www.ncbi.nlm.nih.gov/pubmed/27554046 http://dx.doi.org/10.1111/cas.13062 |
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