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Lovastatin fails to improve motor performance and survival in methyl-CpG-binding protein2-null mice

Previous studies provided evidence for the alteration of brain cholesterol homeostasis in 129.Mecp2-null mice, an experimental model of Rett syndrome. The efficacy of statins in improving motor symptoms and prolonging survival of mutant mice suggested a potential role of statins in the therapy of Re...

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Detalles Bibliográficos
Autores principales:	Villani, Claudia, Sacchetti, Giuseppina, Bagnati, Renzo, Passoni, Alice, Fusco, Federica, Carli, Mirjana, Invernizzi, Roberto William
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2016
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5132339/ https://www.ncbi.nlm.nih.gov/pubmed/27892851 http://dx.doi.org/10.7554/eLife.22409

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