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Hand2 inhibits kidney specification while promoting vein formation within the posterior mesoderm

Proper organogenesis depends upon defining the precise dimensions of organ progenitor territories. Kidney progenitors originate within the intermediate mesoderm (IM), but the pathways that set the boundaries of the IM are poorly understood. Here, we show that the bHLH transcription factor Hand2 limi...

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Detalles Bibliográficos
Autores principales: Perens, Elliot A, Garavito-Aguilar, Zayra V, Guio-Vega, Gina P, Peña, Karen T, Schindler, Yocheved L, Yelon, Deborah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5132343/
https://www.ncbi.nlm.nih.gov/pubmed/27805568
http://dx.doi.org/10.7554/eLife.19941