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Hand2 inhibits kidney specification while promoting vein formation within the posterior mesoderm
Proper organogenesis depends upon defining the precise dimensions of organ progenitor territories. Kidney progenitors originate within the intermediate mesoderm (IM), but the pathways that set the boundaries of the IM are poorly understood. Here, we show that the bHLH transcription factor Hand2 limi...
Autores principales: | Perens, Elliot A, Garavito-Aguilar, Zayra V, Guio-Vega, Gina P, Peña, Karen T, Schindler, Yocheved L, Yelon, Deborah |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5132343/ https://www.ncbi.nlm.nih.gov/pubmed/27805568 http://dx.doi.org/10.7554/eLife.19941 |
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