A Herpesviral induction of RAE-1 NKG2D ligand expression occurs through release of HDAC mediated repression

Natural Killer (NK) cells are essential for control of viral infection and cancer. NK cells express NKG2D, an activating receptor that directly recognizes NKG2D ligands. These are expressed at low level on healthy cells, but are induced by stresses like infection and transformation. The physiologica...

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Detalles Bibliográficos
Autores principales: Greene, Trever T, Tokuyama, Maria, Knudsen, Giselle M, Kunz, Michele, Lin, James, Greninger, Alexander L, DeFilippis, Victor R, DeRisi, Joseph L, Raulet, David H, Coscoy, Laurent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5132344/
https://www.ncbi.nlm.nih.gov/pubmed/27874833
http://dx.doi.org/10.7554/eLife.14749

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