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Disruption of Protein Mannosylation Affects Candida guilliermondii Cell Wall, Immune Sensing, and Virulence

The fungal cell wall contains glycoproteins that interact with the host immune system. In the prominent pathogenic yeast Candida albicans, Pmr1 acts as a Golgi-resident ion pump that provides cofactors to mannosyltransferases, regulating the synthesis of mannans attached to glycoproteins. To gain in...

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Detalles Bibliográficos
Autores principales: Navarro-Arias, María J., Defosse, Tatiana A., Dementhon, Karine, Csonka, Katalin, Mellado-Mojica, Erika, Dias Valério, Aline, González-Hernández, Roberto J., Courdavault, Vincent, Clastre, Marc, Hernández, Nahúm V., Pérez-García, Luis A., Singh, Dhirendra K., Vizler, Csaba, Gácser, Attila, Almeida, Ricardo S., Noël, Thierry, López, Mercedes G., Papon, Nicolas, Mora-Montes, Héctor M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133257/
https://www.ncbi.nlm.nih.gov/pubmed/27994582
http://dx.doi.org/10.3389/fmicb.2016.01951