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Treatment with FGFR2-IIIc monoclonal antibody suppresses weight gain and adiposity in KKA(y) mice
Expression of β-Kotho, fibroblast growth factor receptor (FGFR)-1c and 2c, which bind FGF21, is decreased in the white adipose tissue of obese mice. The aim of the present study was to determine the role of FGFR2c in the development of obesity and diabetes in KKA(y) mice. Treatment with mouse monocl...
Autores principales: | Nonogaki, K, Kaji, T, Yamazaki, T, Murakami, Mari |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133360/ https://www.ncbi.nlm.nih.gov/pubmed/27892934 http://dx.doi.org/10.1038/nutd.2016.41 |
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