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Transglutaminase 2 is dispensable but required for the survival of mice in dextran sulfate sodium-induced colitis

Transglutaminase 2 (TG2) is a ubiquitously expressed enzyme that catalyzes crosslinking, polyamination or deamidation of glutamine residues in proteins. It has been reported that TG2 is involved in the pathogenesis of various inflammatory diseases including celiac disease, pulmonary fibrosis, cystic...

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Detalles Bibliográficos
Autores principales: Jeong, Eui Man, Son, Young Hoon, Choi, Yewon, Kim, Jin-Hee, Lee, Jin-Haeng, Cho, Sung-Yup, Kim, In-Gyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133373/
https://www.ncbi.nlm.nih.gov/pubmed/27811936
http://dx.doi.org/10.1038/emm.2016.95