Cargando…
Immunoproteasome induction is suppressed in hepatitis C virus-infected cells in a protein kinase R-dependent manner
By changing the relative abundance of generated antigenic peptides through alterations in the proteolytic activity, interferon (IFN)-γ-induced immunoproteasomes influence the outcome of CD8(+) cytotoxic T lymphocyte responses. In the present study, we investigated the effects of hepatitis C virus (H...
Autores principales: | Oh, In Soo, Textoris-Taube, Kathrin, Sung, Pil Soo, Kang, Wonseok, Gorny, Xenia, Kähne, Thilo, Hong, Seon-Hui, Choi, Young Joon, Cammann, Clemens, Naumann, Michael, Kim, Jong Hoon, Park, Su-Hyung, Yoo, Ook Joon, Kloetzel, Peter M, Seifert, Ulrike, Shin, Eui-Cheol |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133375/ https://www.ncbi.nlm.nih.gov/pubmed/27833096 http://dx.doi.org/10.1038/emm.2016.98 |
Ejemplares similares
-
Low Neurotoxicity of ONX-0914 Supports the Idea of Specific Immunoproteasome Inhibition as a Side-Effect-Limiting, Therapeutic Strategy
por: von Brzezinski, Laura, et al.
Publicado: (2017) -
The Immunoproteasome Subunits LMP2, LMP7 and MECL-1 Are Crucial Along the Induction of Cerebral Toxoplasmosis
por: French, Timothy, et al.
Publicado: (2021) -
Immunoproteasome LMP2 60HH Variant Alters MBP Epitope Generation and Reduces the Risk to Develop Multiple Sclerosis in Italian Female Population
por: Mishto, Michele, et al.
Publicado: (2010) -
The 20S Proteasome Splicing Activity Discovered by SpliceMet
por: Liepe, Juliane, et al.
Publicado: (2010) -
Immunoproteasome function maintains oncogenic gene expression in KMT2A-complex driven leukemia
por: Tubío-Santamaría, Nuria, et al.
Publicado: (2023)