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Modeling the prevention of colorectal cancer from the combined impact of host and behavioral risk factors

PURPOSE: This study investigated the utility of modeling modifiable lifestyle risk factors in addition to genetic variation in colorectal cancer (CRC) screening/prevention. METHODS: We derived a polygenic risk score for CRC susceptibility variants in combination with the established nongenetic risk...

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Detalles Bibliográficos
Autores principales: Frampton, Matthew, Houlston, Richard S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133376/
https://www.ncbi.nlm.nih.gov/pubmed/27490113
http://dx.doi.org/10.1038/gim.2016.101