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Peripheral self-reactivity regulates antigen-specific CD8 T-cell responses and cell division under physiological conditions

T-cell identity is established by the expression of a clonotypic T-cell receptor (TCR), generated by somatic rearrangement of TCRα and β genes. The properties of the TCR determine both the degree of self-reactivity and the repertoire of antigens that can be recognized. For CD8 T cells, the relations...

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Detalles Bibliográficos
Autores principales:	Swee, Lee Kim, Tan, Zhen Wei, Sanecka, Anna, Yoshida, Nagisa, Patel, Harshil, Grotenbreg, Gijsbert, Frickel, Eva-Maria, Ploegh, Hidde L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133449/ https://www.ncbi.nlm.nih.gov/pubmed/27881740 http://dx.doi.org/10.1098/rsob.160293

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