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J-curve relation between daytime nap duration and type 2 diabetes or metabolic syndrome: A dose-response meta-analysis
Adequate sleep is important for good health, but it is not always easy to achieve because of social factors. Daytime napping is widely prevalent around the world. We performed a meta-analysis to investigate the association between napping (or excessive daytime sleepiness: EDS) and the risk of type 2...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133463/ https://www.ncbi.nlm.nih.gov/pubmed/27909305 http://dx.doi.org/10.1038/srep38075 |
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author | Yamada, Tomohide Shojima, Nobuhiro Yamauchi, Toshimasa Kadowaki, Takashi |
author_facet | Yamada, Tomohide Shojima, Nobuhiro Yamauchi, Toshimasa Kadowaki, Takashi |
author_sort | Yamada, Tomohide |
collection | PubMed |
description | Adequate sleep is important for good health, but it is not always easy to achieve because of social factors. Daytime napping is widely prevalent around the world. We performed a meta-analysis to investigate the association between napping (or excessive daytime sleepiness: EDS) and the risk of type 2 diabetes or metabolic syndrome, and to quantify the potential dose-response relation using cubic spline models. Electronic databases were searched for articles published up to 2016, with 288,883 Asian and Western subjects. Pooled analysis revealed that a long nap (≥60 min/day) and EDS were each significantly associated with an increased risk of type 2 diabetes versus no nap or no EDS (odds ratio 1.46 (95% CI 1.23–1.74, p < 0.01) for a long nap and 2.00 (1.58–2.53) for EDS). In contrast, a short nap (<60 min/day) was not associated with diabetes (p = 0.75). Dose-response meta-analysis showed a J-curve relation between nap time and the risk of diabetes or metabolic syndrome, with no effect of napping up to about 40 minutes/day, followed by a sharp increase in risk at longer nap times. In summary, longer napping is associated with an increased risk of metabolic disease. Further studies are needed to confirm the benefit of a short nap. |
format | Online Article Text |
id | pubmed-5133463 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Nature Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-51334632017-01-27 J-curve relation between daytime nap duration and type 2 diabetes or metabolic syndrome: A dose-response meta-analysis Yamada, Tomohide Shojima, Nobuhiro Yamauchi, Toshimasa Kadowaki, Takashi Sci Rep Article Adequate sleep is important for good health, but it is not always easy to achieve because of social factors. Daytime napping is widely prevalent around the world. We performed a meta-analysis to investigate the association between napping (or excessive daytime sleepiness: EDS) and the risk of type 2 diabetes or metabolic syndrome, and to quantify the potential dose-response relation using cubic spline models. Electronic databases were searched for articles published up to 2016, with 288,883 Asian and Western subjects. Pooled analysis revealed that a long nap (≥60 min/day) and EDS were each significantly associated with an increased risk of type 2 diabetes versus no nap or no EDS (odds ratio 1.46 (95% CI 1.23–1.74, p < 0.01) for a long nap and 2.00 (1.58–2.53) for EDS). In contrast, a short nap (<60 min/day) was not associated with diabetes (p = 0.75). Dose-response meta-analysis showed a J-curve relation between nap time and the risk of diabetes or metabolic syndrome, with no effect of napping up to about 40 minutes/day, followed by a sharp increase in risk at longer nap times. In summary, longer napping is associated with an increased risk of metabolic disease. Further studies are needed to confirm the benefit of a short nap. Nature Publishing Group 2016-12-02 /pmc/articles/PMC5133463/ /pubmed/27909305 http://dx.doi.org/10.1038/srep38075 Text en Copyright © 2016, The Author(s) http://creativecommons.org/licenses/by/4.0/ This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ |
spellingShingle | Article Yamada, Tomohide Shojima, Nobuhiro Yamauchi, Toshimasa Kadowaki, Takashi J-curve relation between daytime nap duration and type 2 diabetes or metabolic syndrome: A dose-response meta-analysis |
title | J-curve relation between daytime nap duration and type 2 diabetes or metabolic syndrome: A dose-response meta-analysis |
title_full | J-curve relation between daytime nap duration and type 2 diabetes or metabolic syndrome: A dose-response meta-analysis |
title_fullStr | J-curve relation between daytime nap duration and type 2 diabetes or metabolic syndrome: A dose-response meta-analysis |
title_full_unstemmed | J-curve relation between daytime nap duration and type 2 diabetes or metabolic syndrome: A dose-response meta-analysis |
title_short | J-curve relation between daytime nap duration and type 2 diabetes or metabolic syndrome: A dose-response meta-analysis |
title_sort | j-curve relation between daytime nap duration and type 2 diabetes or metabolic syndrome: a dose-response meta-analysis |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133463/ https://www.ncbi.nlm.nih.gov/pubmed/27909305 http://dx.doi.org/10.1038/srep38075 |
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