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Insights into the Phosphoryl Transfer Mechanism of Human Ubiquitous Mitochondrial Creatine Kinase

Human ubiquitous mitochondrial creatine kinase (uMtCK) is responsible for the regulation of cellular energy metabolism. To investigate the phosphoryl-transfer mechanism catalyzed by human uMtCK, in this work, molecular dynamic simulations of uMtCK∙ATP-Mg(2+)∙creatine complex and quantum mechanism ca...

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Detalles Bibliográficos
Autores principales:	Li, Quanjie, Fan, Shuai, Li, Xiaoyu, Jin, Yuanyuan, He, Weiqing, Zhou, Jinming, Cen, Shan, Yang, ZhaoYong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133464/ https://www.ncbi.nlm.nih.gov/pubmed/27909311 http://dx.doi.org/10.1038/srep38088

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