Cargando…

Data describing the association between rs266729 polymorphism inadiponectin promoter gene and Type 2 Diabetes Mellitus

This article investigates whether there is an association between the rs266729 polymorphism in adiponectin promoter gene with metabolic parameters and disease status in 300 type 2 diabetes patients and 300 healthy adults from Jahrom city, Iran. The variants (G/C) were tested by polymerase chain reac...

Descripción completa

Detalles Bibliográficos
Autores principales: Erfanian, Saiedeh, Moradzadeh, Malihe, Solhjoo, Kavous, Jahromi, Abdolreza Sotoodeh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133470/
https://www.ncbi.nlm.nih.gov/pubmed/27942572
http://dx.doi.org/10.1016/j.dib.2016.11.040
Descripción
Sumario:This article investigates whether there is an association between the rs266729 polymorphism in adiponectin promoter gene with metabolic parameters and disease status in 300 type 2 diabetes patients and 300 healthy adults from Jahrom city, Iran. The variants (G/C) were tested by polymerase chain reaction-restriction fragment length polymorphism method (RFLP) and metabolic parameters (glucose, cholesterol, HDL and LDL cholesterol) were measured using biochemical methods. However, no differences were detected between the haplotypes investigated, and the data obtained from our lab shown association of the ADIPOQ promoter polymorphism neither with biochemical parameters, nor with disease status.