Comparison of parametric and machine methods for variable selection in simulated Genetic Analysis Workshop 19 data

Current findings from genetic studies of complex human traits often do not explain a large proportion of the estimated variation of these traits due to genetic factors. This could be, in part, due to overly stringent significance thresholds in traditional statistical methods, such as linear and logi...

Descripción completa

Detalles Bibliográficos
Autores principales: Holzinger, Emily R., Szymczak, Silke, Malley, James, Pugh, Elizabeth W., Ling, Hua, Griffith, Sean, Zhang, Peng, Li, Qing, Cropp, Cheryl D., Bailey-Wilson, Joan E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Proceedings
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133476/
https://www.ncbi.nlm.nih.gov/pubmed/27980627
http://dx.doi.org/10.1186/s12919-016-0021-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133476/
https://www.ncbi.nlm.nih.gov/pubmed/27980627
http://dx.doi.org/10.1186/s12919-016-0021-1

Ejemplares similares