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Identifying rare and common variants with Bayesian variable selection

BACKGROUND: Recent advances in next-generation sequencing technologies have made it possible to generate large amounts of sequence data with rare variants in a cost-effective way. Yet, the statistical aspect of testing disease association of rare variants is quite challenging as the typical assumpti...

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Detalles Bibliográficos
Autor principal: Oh, Cheongeun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133477/
https://www.ncbi.nlm.nih.gov/pubmed/27980665
http://dx.doi.org/10.1186/s12919-016-0059-0