Using gene expression data to identify causal pathways between genotype and phenotype in a complex disease: application to Genetic Analysis Workshop 19

We explore causal relationships between genotype, gene expression and phenotype in the Genetic Analysis Workshop 19 data. We compare the use of structural equation modeling and a Bayesian unified framework approach to infer the most likely causal models that gave rise to the data. Testing an exhaust...

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Detalles Bibliográficos
Autores principales: Ainsworth, Holly F., Cordell, Heather J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Proceedings
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133478/
https://www.ncbi.nlm.nih.gov/pubmed/27980615
http://dx.doi.org/10.1186/s12919-016-0009-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133478/
https://www.ncbi.nlm.nih.gov/pubmed/27980615
http://dx.doi.org/10.1186/s12919-016-0009-x

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