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A variance component method for integrated pathway analysis of gene expression data

BACKGROUND: The application of pathway and gene-set based analyses to high-throughput data is increasingly common and represents an effort to understand underlying biology where single-gene or single-marker analyses have failed. Many such analyses rely on the a priori identification of genes associa...

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Detalles Bibliográficos
Autores principales: Quillen, Ellen E., Blangero, John, Almasy, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133490/
https://www.ncbi.nlm.nih.gov/pubmed/27980659
http://dx.doi.org/10.1186/s12919-016-0053-6