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Powerful association test combining rare variant and gene expression using family data from Genetic Analysis Workshop 19

BACKGROUND: Genetic association studies aim to test for disease or trait association with genetic variants, either throughout the human genome or in regions of interest. However, for most diseases and traits, the combined effects of associated genetic variants explain only a small proportion of the...

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Detalles Bibliográficos
Autores principales: Ho, Yen-Yi, Guan, Weihua, O’Connell, Michael, Basu, Saonli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133497/
https://www.ncbi.nlm.nih.gov/pubmed/27980645
http://dx.doi.org/10.1186/s12919-016-0039-4