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Powerful association test combining rare variant and gene expression using family data from Genetic Analysis Workshop 19
BACKGROUND: Genetic association studies aim to test for disease or trait association with genetic variants, either throughout the human genome or in regions of interest. However, for most diseases and traits, the combined effects of associated genetic variants explain only a small proportion of the...
Autores principales: | Ho, Yen-Yi, Guan, Weihua, O’Connell, Michael, Basu, Saonli |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133497/ https://www.ncbi.nlm.nih.gov/pubmed/27980645 http://dx.doi.org/10.1186/s12919-016-0039-4 |
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