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A combined association test for rare variants using family and case-control data
Statistical association tests for rare variants can be classified as the burden approach and the sequence kernel association test (SKAT) approach. The burden and SKAT approaches, originally developed for case–control analysis, have also been extended to family-based tests. In the presence of both ca...
Autores principales: | Lin, Peng-Lin, Tsai, Wei-Yun, Chung, Ren-Hua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133518/ https://www.ncbi.nlm.nih.gov/pubmed/27980639 http://dx.doi.org/10.1186/s12919-016-0033-x |
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