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Independent test assessment using the extreme value distribution theory

The new generation of whole genome sequencing platforms offers great possibilities and challenges for dissecting the genetic basis of complex traits. With a very high number of sequence variants, a naïve multiple hypothesis threshold correction hinders the identification of reliable associations by...

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Detalles Bibliográficos
Autores principales:	Almeida, Marcio, Blondell, Lucy, Peralta, Juan M., Kent, Jack W., Jun, Goo, Teslovich, Tanya M., Fuchsberger, Christian, Wood, Andrew R., Manning, Alisa K., Frayling, Timothy M., Cingolani, Pablo E., Sladek, Robert, Dyer, Thomas D., Abecasis, Goncalo, Duggirala, Ravindranath, Blangero, John
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Proceedings
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133519/ https://www.ncbi.nlm.nih.gov/pubmed/27980644 http://dx.doi.org/10.1186/s12919-016-0038-5

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