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Estimating relationships between phenotypes and subjects drawn from admixed families

BACKGROUND: Estimating relationships among subjects in a sample, within family structures or caused by population substructure, is complicated in admixed populations. Inaccurate allele frequencies can bias both kinship estimates and tests for association between subjects and a phenotype. We analyzed...

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Detalles Bibliográficos
Autores principales:	Blue, Elizabeth M., Brown, Lisa A., Conomos, Matthew P., Kirk, Jennifer L., Nato, Alejandro Q., Popejoy, Alice B., Raffa, Jesse, Ranola, John, Wijsman, Ellen M., Thornton, Timothy
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Proceedings
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133521/ https://www.ncbi.nlm.nih.gov/pubmed/27980662 http://dx.doi.org/10.1186/s12919-016-0056-3

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