Transmission and decorrelation methods for detecting rare variants using sequencing data from related individuals

BACKGROUND: Advances in whole genome sequencing have enabled the investigation of rare variants, which could explain some of the missing heritability that genome-wide association studies are unable to detect. Most methods to detect associations with rare variants are developed for unrelated individu...

Descripción completa

Detalles Bibliográficos
Autores principales: Darst, Burcu F., Engelman, Corinne D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Proceedings
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133523/
https://www.ncbi.nlm.nih.gov/pubmed/27980637
http://dx.doi.org/10.1186/s12919-016-0031-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133523/
https://www.ncbi.nlm.nih.gov/pubmed/27980637
http://dx.doi.org/10.1186/s12919-016-0031-z

Ejemplares similares