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Transmission and decorrelation methods for detecting rare variants using sequencing data from related individuals
BACKGROUND: Advances in whole genome sequencing have enabled the investigation of rare variants, which could explain some of the missing heritability that genome-wide association studies are unable to detect. Most methods to detect associations with rare variants are developed for unrelated individu...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133523/ https://www.ncbi.nlm.nih.gov/pubmed/27980637 http://dx.doi.org/10.1186/s12919-016-0031-z |