Cargando…
On combining family- and population-based sequencing data
Several statistical group-based approaches have been proposed to detect effects of variation within a gene for each of the population- and family-based designs. However, unified tests to combine gene-phenotype associations obtained from these 2 study designs are not yet well established. In this stu...
Autores principales: | Katsumata, Yuriko, Fardo, David W. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133531/ https://www.ncbi.nlm.nih.gov/pubmed/27980632 http://dx.doi.org/10.1186/s12919-016-0026-9 |
Ejemplares similares
-
Exploration and comparison of methods for combining population- and family-based genetic association using the Genetic Analysis Workshop 17 mini-exome
por: Fardo, David W, et al.
Publicado: (2011) -
A 2-step penalized regression method for family-based next-generation sequencing association studies
por: Ding, Xiuhua, et al.
Publicado: (2014) -
Causal effect estimation in sequencing studies: a Bayesian method to account for confounder adjustment uncertainty
por: Wang, Chi, et al.
Publicado: (2016) -
Comparing performance of non–tree-based and tree-based association mapping methods
por: Thompson, Katherine L., et al.
Publicado: (2016) -
A comparative analysis of family-based and population-based association tests using whole genome sequence data
por: Zhou, Jin J, et al.
Publicado: (2014)