Transmission of Multiple HIV-1 Subtype C Transmitted/founder Viruses into the Same Recipients Was not Determined by Modest Phenotypic Differences

A severe bottleneck exists during HIV-1 mucosal transmission. However, viral properties that determine HIV-1 transmissibility are not fully elucidated. We identified multiple transmitted/founder (T/F) viruses in six HIV-1-infected subjects by analyzing whole genome sequences. Comparison of biologica...

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Detalles Bibliográficos
Autores principales: Song, Hongshuo, Hora, Bhavna, Giorgi, Elena E., Kumar, Amit, Cai, Fangping, Bhattacharya, Tanmoy, Perelson, Alan S., Gao, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133561/
https://www.ncbi.nlm.nih.gov/pubmed/27909304
http://dx.doi.org/10.1038/srep38130

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133561/
https://www.ncbi.nlm.nih.gov/pubmed/27909304
http://dx.doi.org/10.1038/srep38130

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