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Protein expression from unintegrated HIV-1 DNA introduces bias in primary in vitro post-integration latency models

To understand the persistence of latently HIV-1 infected cells in virally suppressed infected patients, a number of in vitro models of HIV latency have been developed. In an attempt to mimic the in vivo situation as closely as possible, several models use primary cells and replication-competent viru...

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Detalles Bibliográficos
Autores principales: Bonczkowski, Pawel, De Scheerder, Marie-Angélique, Malatinkova, Eva, Borch, Alexandra, Melkova, Zora, Koenig, Renate, De Spiegelaere, Ward, Vandekerckhove, Linos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133580/
https://www.ncbi.nlm.nih.gov/pubmed/27910923
http://dx.doi.org/10.1038/srep38329

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