Disentangling the roles of cholesterol and CD59 in intermedilysin pore formation

The plasma membrane provides an essential barrier, shielding a cell from the pressures of its external environment. Pore-forming proteins, deployed by both hosts and pathogens alike, breach this barrier to lyse target cells. Intermedilysin is a cholesterol-dependent cytolysin that requires the human...

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Detalles Bibliográficos
Autores principales: Boyd, Courtney M., Parsons, Edward S., Smith, Richard A. G., Seddon, John M., Ces, Oscar, Bubeck, Doryen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133593/
https://www.ncbi.nlm.nih.gov/pubmed/27910935
http://dx.doi.org/10.1038/srep38446

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133593/
https://www.ncbi.nlm.nih.gov/pubmed/27910935
http://dx.doi.org/10.1038/srep38446

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