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The Expression and Clinical Outcome of pCHK2-Thr68 and pCDC25C-Ser216 in Breast Cancer

Checkpoint kinase 2 (CHK2) and cell division cycle 25C (CDC25C) are two proteins involved in the DNA damage response pathway, playing essential roles in maintaining genome integrity. As one of the major hallmarks of abnormal cellular division, genomic instability occurs in most cancers. In this stud...

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Detalles Bibliográficos
Autores principales: Jiang, Huayong, Wang, Bin, Zhang, Fuli, Qian, Yuanyu, Chuang, Chia-Chen, Ying, Mingzhen, Wang, Yajie, Zuo, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133804/
https://www.ncbi.nlm.nih.gov/pubmed/27801830
http://dx.doi.org/10.3390/ijms17111803