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The Effect of Everolimus in an In Vitro Model of Triple Negative Breast Cancer and Osteoclasts

Metastatic bone disease has a major impact on morbidity of breast cancer (BC) patients. Alterations in mTOR signaling are involved both in cancer progression and in osteoclast differentiation. The purpose of this study was to assess the role of mTOR inhibitor Everolimus (Eve) on osteoclastogenesis i...

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Detalles Bibliográficos
Autores principales: Mercatali, Laura, Spadazzi, Chiara, Miserocchi, Giacomo, Liverani, Chiara, De Vita, Alessandro, Bongiovanni, Alberto, Recine, Federica, Amadori, Dino, Ibrahim, Toni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133828/
https://www.ncbi.nlm.nih.gov/pubmed/27809291
http://dx.doi.org/10.3390/ijms17111827