Cargando…

The Multifaceted Roles of PI3Kγ in Hypertension, Vascular Biology, and Inflammation

PI3Kγ is a multifaceted protein, crucially involved in cardiovascular and immune systems. Several studies described the biological and physiological functions of this enzyme in the regulation of cardiovascular system, while others stressed its role in the modulation of immunity. Although PI3Kγ has b...

Descripción completa

Detalles Bibliográficos
Autores principales:	Perrotta, Marialuisa, Lembo, Giuseppe, Carnevale, Daniela
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2016
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133858/ https://www.ncbi.nlm.nih.gov/pubmed/27834808 http://dx.doi.org/10.3390/ijms17111858

Ejemplares similares

Hypertension and Dementia: Epidemiological and Experimental Evidence Revealing a Detrimental Relationship
por: Perrotta, Marialuisa, et al.
Publicado: (2016)

Chronic 3D Vascular-Immune Interface Established by Coculturing Pressurized Resistance Arteries and Immune Cells
por: Carnevale, Daniela, et al.
Publicado: (2021)

The Spleen: A Hub Connecting Nervous and Immune Systems in Cardiovascular and Metabolic Diseases
por: Lori, Andrea, et al.
Publicado: (2017)

A Focused Review of Neural Recording and Stimulation Techniques With Immune-Modulatory Targets
por: Carnevale, Lorenzo, et al.
Publicado: (2021)

A cholinergic-sympathetic pathway primes immunity in hypertension and mediates brain-to-spleen communication
por: Carnevale, Daniela, et al.
Publicado: (2016)

Mouse models of cerebral injury and cognitive impairment in hypertension
por: Perrotta, Marialuisa, et al.
Publicado: (2023)

Lack of kinase-independent activity of PI3Kγ in locus coeruleus induces ADHD symptoms through increased CREB signaling
por: D'Andrea, Ivana, et al.
Publicado: (2015)

PI3Kinases in Diabetes Mellitus and Its Related Complications
por: Maffei, Angelo, et al.
Publicado: (2018)

PlGF, immune system and hypertension
por: Carnevale, Daniela, et al.
Publicado: (2015)

Celiac Vagus Nerve Stimulation Recapitulates Angiotensin II-Induced Splenic Noradrenergic Activation, Driving Egress of CD8 Effector Cells
por: Carnevale, Lorenzo, et al.
Publicado: (2020)

Function, Regulation and Biological Roles of PI3Kγ Variants
por: Nürnberg, Bernd, et al.
Publicado: (2019)

Protection from angiotensin II–mediated vasculotoxic and hypertensive response in mice lacking PI3Kγ
por: Vecchione, Carmine, et al.
Publicado: (2005)

Innovative MRI Techniques in Neuroimaging Approaches for Cerebrovascular Diseases and Vascular Cognitive Impairment
por: Carnevale, Lorenzo, et al.
Publicado: (2019)

The multifaceted role of plasminogen in inflammation
por: Heissig, Beate, et al.
Publicado: (2020)

Roles of PI3Kγ and PI3Kδ in mantle cell lymphoma proliferation and migration contributing to efficacy of the PI3Kγ/δ inhibitor duvelisib
por: Till, Kathleen J., et al.
Publicado: (2023)

The role of PI3Kγ in metabolism and macrophage activation
por: Solinas, Giovanni, et al.
Publicado: (2017)

Regulation of T cell alloimmunity by PI3Kγ and PI3Kδ
por: Uehara, Mayuko, et al.
Publicado: (2017)

More Paths to PI3Kγ
por: Stephens, Len, et al.
Publicado: (2013)

PI3Kγ promotes obesity-associated hepatocellular carcinoma by regulating metabolism and inflammation
por: Becattini, Barbara, et al.
Publicado: (2021)

Multifaceted role of β-arrestins in inflammation and disease
por: Sharma, Deepika, et al.
Publicado: (2015)

Multifaceted Physiological Roles of Adiponectin in Inflammation and Diseases
por: Choi, Hyung Muk, et al.
Publicado: (2020)

Recent Advances in Lupus B Cell Biology: PI3K, IFNγ, and Chromatin
por: Bacalao, Maria A., et al.
Publicado: (2021)

Role of Peroxisome Proliferator-Activated Receptor-γ in Vascular Inflammation
por: Ohshima, Kousei, et al.
Publicado: (2012)

γ-Secretase: a multifaceted regulator of angiogenesis
por: Boulton, Michael E, et al.
Publicado: (2008)

The Biological Role of PI3K Pathway in Lung Cancer
por: Sarris, Evangelos G., et al.
Publicado: (2012)

Chronic Type A aortic dissection: could surgical intervention be guided by molecular markers?
por: Carnevale, Daniela, et al.
Publicado: (2011)

Roles of phosphatidyl inositol 3 kinase gamma (PI3Kγ) in respiratory diseases
por: Sala, Valentina, et al.
Publicado: (2021)

Localizing the lipid products of PI3Kγ in neutrophils
por: Norton, Laura, et al.
Publicado: (2016)

The emerging multifaceted role of PINK1 in cancer biology
por: Wang, Meng, et al.
Publicado: (2022)

Role of Cox-2 in Vascular Inflammation: An Experimental Model of Metabolic Syndrome
por: Renna, Nicolás F., et al.
Publicado: (2013)

Vitamin K–Dependent Matrix Gla Protein as Multifaceted Protector of Vascular and Tissue Integrity
por: Wei, Fang-Fei, et al.
Publicado: (2019)

Multifaceted Roles of CD5L in Infectious and Sterile Inflammation
por: Sanchez-Moral, Lidia, et al.
Publicado: (2021)

The Multifaceted Biology of PCSK9
por: Seidah, Nabil G, et al.
Publicado: (2021)

Roles of Inflammation, Oxidative Stress, and Vascular Dysfunction in Hypertension
por: Dinh, Quynh N., et al.
Publicado: (2014)

Breast Cancer Biology: The Multifaceted Roles of Mesenchymal Stem Cells
por: Patel, Shyam A., et al.
Publicado: (2008)

Emerging multifaceted roles of BAP1 complexes in biological processes
por: Szczepanski, Aileen Patricia, et al.
Publicado: (2021)

Role of Renin-Angiotensin System and Oxidative Stress on Vascular Inflammation in Insulin Resistence Model
por: Renna, N. F., et al.
Publicado: (2013)

The PI3K-Akt pathway is a multifaceted regulator of the macrophage response to diverse group B Streptococcus isolates
por: De-Leon-Lopez, Yadira S., et al.
Publicado: (2023)

The Role of the Pathogen Dose and PI3Kγ in Immunometabolic Reprogramming of Microglia for Innate Immune Memory
por: Lajqi, Trim, et al.
Publicado: (2021)

Activated PI3Kinase Delta Syndrome—A Multifaceted Disease
por: Thouenon, Romane, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_bqs262e61ou9onum31jdobbgil