Cargando…

TRAIL (TNF-related apoptosis-inducing ligand) inhibits human adipocyte differentiation via caspase-mediated downregulation of adipogenic transcription factors

Tumor necrosis factor-α (TNFα) and other ligands of the TNF superfamily are potent regulators of adipose tissue metabolism and play a crucial role in the obesity-induced inflammation of adipose tissue. Adipose tissue expression levels of TRAIL (TNF-related apoptosis-inducing ligand) and its receptor...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zoller, Verena, Funcke, Jan-Bernd, Keuper, Michaela, Abd El Hay, Muad, Debatin, Klaus-Michael, Wabitsch, Martin, Fischer-Posovszky, Pamela
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133965/ https://www.ncbi.nlm.nih.gov/pubmed/27735943 http://dx.doi.org/10.1038/cddis.2016.286

Ejemplares similares

Trail (TNF-related apoptosis-inducing ligand) induces an inflammatory response in human adipocytes
por: Zoller, Verena, et al.
Publicado: (2017)

TRAIL (TNF-related apoptosis-inducing ligand) regulates adipocyte metabolism by caspase-mediated cleavage of PPARgamma
por: Keuper, M, et al.
Publicado: (2013)

Interleukin-1β Downregulates RBP4 Secretion in Human Adipocytes
por: Kotnik, Primoz, et al.
Publicado: (2013)

Elevated UCP1 levels are sufficient to improve glucose uptake in human white adipocytes
por: Tews, D., et al.
Publicado: (2019)

miR-146a-mediated suppression of the inflammatory response in human adipocytes
por: Roos, Julian, et al.
Publicado: (2016)

THP-1 Macrophages and SGBS Adipocytes – A New Human in vitro Model System of Inflamed Adipose Tissue
por: Keuper, Michaela, et al.
Publicado: (2011)

Monogenic forms of childhood obesity due to mutations in the leptin gene
por: Funcke, Jan-Bernd, et al.
Publicado: (2014)

CD90 Is Dispensable for White and Beige/Brown Adipocyte Differentiation
por: Dahlhaus, Meike, et al.
Publicado: (2020)

Establishment of Lipofection for Studying miRNA Function in Human Adipocytes
por: Enlund, Eveliina, et al.
Publicado: (2014)

20 Years with SGBS cells - a versatile in vitro model of human adipocyte biology
por: Tews, Daniel, et al.
Publicado: (2022)

On the role of macrophages in the control of adipocyte energy metabolism
por: Keuper, Michaela
Publicado: (2019)

Adipocytes in hematopoiesis and acute leukemia: friends, enemies, or innocent bystanders?
por: Zinngrebe, Julia, et al.
Publicado: (2020)

Activated macrophages control human adipocyte mitochondrial bioenergetics via secreted factors
por: Keuper, Michaela, et al.
Publicado: (2017)

Estimated prevalence of potentially damaging variants in the leptin gene
por: Nunziata, Adriana, et al.
Publicado: (2017)

Thermogenic Activation Downregulates High Mitophagy Rate in Human Masked and Mature Beige Adipocytes
por: Szatmári-Tóth, Mária, et al.
Publicado: (2020)

Lipid Nanoparticles as a Shuttle for Anti-Adipogenic miRNAs to Human Adipocytes
por: Schachner-Nedherer, Anna-Laurence, et al.
Publicado: (2023)

Resveratrol Suppresses PAI-1 Gene Expression in a Human In Vitro Model of Inflamed Adipose Tissue
por: Zagotta, Ivana, et al.
Publicado: (2013)

Age- and BMI-Associated Expression of Angiogenic Factors in White Adipose Tissue of Children
por: Gaebler, Niklas, et al.
Publicado: (2019)

miR-146a regulates insulin sensitivity via NPR3
por: Roos, Julian, et al.
Publicado: (2020)

Latent TGFβ-binding proteins regulate UCP1 expression and function via TGFβ2
por: Halbgebauer, D., et al.
Publicado: (2021)

Impact of X-ray Exposure on the Proliferation and Differentiation of Human Pre-Adipocytes
por: Shreder, Kateryna, et al.
Publicado: (2018)

Anti-Adipogenic Effect of Alchemilla monticola is Mediated Via PI3K/AKT Signaling Inhibition in Human Adipocytes
por: Mladenova, Saveta G., et al.
Publicado: (2021)

Different anti-adipogenic effects of bio-compounds on primary visceral pre-adipocytes and adipocytes
por: Colitti, Monica, et al.
Publicado: (2016)

Brown adipogenic potential of brown adipocytes and peri-renal adipocytes from human embryo
por: Wu, Nan-Nan, et al.
Publicado: (2016)

Mechanism of TNFα-induced downregulation of salt-inducible kinase 2 in adipocytes
por: Vaváková, Magdaléna, et al.
Publicado: (2023)

Chromium Propionate Enhances Adipogenic Differentiation of Bovine Intramuscular Adipocytes
por: Tokach, Rebecca J., et al.
Publicado: (2015)

Obesity and inflammation: reduced cytokine expression due to resveratrol in a human in vitro model of inflamed adipose tissue
por: Zagotta, Ivana, et al.
Publicado: (2015)

Functional and Phenotypic Characteristics of Human Leptin Receptor Mutations
por: Nunziata, Adriana, et al.
Publicado: (2018)

Artemisia princeps Inhibits Adipogenic Differentiation of 3T3-L1 Pre-Adipocytes via Downregulation of PPARγ and MAPK Pathways
por: Oh, Jung Hwan, et al.
Publicado: (2019)

AQP3 Facilitates Proliferation and Adipogenic Differentiation of Porcine Intramuscular Adipocytes
por: Wang, Xiaoyu, et al.
Publicado: (2020)

Anti-Adipogenic Activity of High-Phenolic Sorghum Brans in Pre-Adipocytes
por: Lee, Hee-Seop, et al.
Publicado: (2022)

TRAIL-β and TRAIL-γ: two novel splice variants of the human TNF-related apoptosis-inducing ligand (TRAIL) without apoptotic potential
por: Krieg, A, et al.
Publicado: (2003)

Differentiating SGBS adipocytes respond to PPARγ stimulation, irisin and BMP7 by functional browning and beige characteristics
por: Klusóczki, Ágnes, et al.
Publicado: (2019)

Adverse bioenergetic effects of N-acyl amino acids in human adipocytes overshadow beneficial mitochondrial uncoupling
por: Herrnhold, Marie, et al.
Publicado: (2023)

Clozapine modifies the differentiation program of human adipocytes inducing browning
por: Kristóf, E, et al.
Publicado: (2016)

Severe Early-Onset Obesity Due to Bioinactive Leptin Caused by a p.N103K Mutation in the Leptin Gene
por: Wabitsch, Martin, et al.
Publicado: (2015)

Toward Marrow Adipocytes: Adipogenic Trajectory of the Bone Marrow Stromal Cell Lineage
por: Matsushita, Yuki, et al.
Publicado: (2022)

Periplasmic Expression of TNF Related Apoptosis Inducing Ligand (TRAIL) in E.coli
por: Tavallaei, Omid, et al.
Publicado: (2015)

Sargassum miyabei Yendo Brown Algae Exert Anti-Oxidative and Anti-AdipogenicEffects on 3T3-L1 Adipocytes by Downregulating PPARγ
por: Kim, Dong Se, et al.
Publicado: (2020)

Compartmentalization of TNF-related apoptosis-inducing ligand (TRAIL) death receptor functions: emerging role of nuclear TRAIL-R2
por: Bertsch, U, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_g3d6u5jsskatfklrqic44u8eki