Attenuated DNA damage repair delays therapy-related myeloid neoplasms in a mouse model

Therapy-related cancers are potentially fatal late life complications for patients who received radio- or chemotherapy. So far, the mouse model showing reduction or delay of these diseases has not been described. We found that the disruption of Aplf in mice moderately attenuated DNA damage repair an...

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Detalles Bibliográficos
Autores principales: Tong, Kit I, Ota, Kazushige, Komuro, Akiyoshi, Ueda, Takeshi, Ito, Akihiko, Anne Koch, C, Okada, Hitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133969/
https://www.ncbi.nlm.nih.gov/pubmed/27711078
http://dx.doi.org/10.1038/cddis.2016.298

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