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Functional KCa1.1 channels are crucial for regulating the proliferation, migration and differentiation of human primary skeletal myoblasts

Myoblasts are mononucleated precursors of myofibers; they persist in mature skeletal muscles for growth and regeneration post injury. During myotonic dystrophy type 1 (DM1), a complex autosomal-dominant neuromuscular disease, the differentiation of skeletal myoblasts into functional myotubes is impa...

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Detalles Bibliográficos
Autores principales: Tajhya, Rajeev B, Hu, Xueyou, Tanner, Mark R, Huq, Redwan, Kongchan, Natee, Neilson, Joel R, Rodney, George G, Horrigan, Frank T, Timchenko, Lubov T, Beeton, Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133989/
https://www.ncbi.nlm.nih.gov/pubmed/27763639
http://dx.doi.org/10.1038/cddis.2016.324