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PARP1 regulates the protein stability and proapoptotic function of HIPK2

Homeodomain-interacting protein kinase 2 (HIPK2) is a nuclear serine/threonine kinase that functions in DNA damage response and development. In the present study, we propose that the protein stability and proapoptotic function of HIPK2 are regulated by poly(ADP-ribose) polymerase 1 (PARP1). We prese...

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Detalles Bibliográficos
Autores principales:	Choi, Jong-Ryoul, Shin, Ki Soon, Choi, Cheol Yong, Kang, Shin Jung
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5134000/ https://www.ncbi.nlm.nih.gov/pubmed/27787517 http://dx.doi.org/10.1038/cddis.2016.345

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