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Diverse drug-resistant subpopulations of Mycobacterium tuberculosis are sustained in continuous culture

Drug resistance to tuberculosis (TB) has become more widespread over the past decade. As such, understanding the emergence and fitness of antibiotic-resistant subpopulations is crucial for the development of new interventions. Here we use a simple mathematical model to explain the differences in the...

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Detalles Bibliográficos
Autores principales: Ayabina, Diepreye, Hendon-Dunn, Charlotte, Bacon, Joanna, Colijn, Caroline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5134024/
https://www.ncbi.nlm.nih.gov/pubmed/27807274
http://dx.doi.org/10.1098/rsif.2016.0745