Granulocyte macrophage colony-stimulating factor receptor α expression and its targeting in antigen-induced arthritis and inflammation

BACKGROUND: Blockade of granulocyte macrophage colony-stimulating factor (GM-CSF) and its receptor (GM-CSFRα) is being successfully tested in trials in rheumatoid arthritis (RA) with clinical results equivalent to those found with neutralization of the current therapeutic targets, TNF and IL-6. To e...

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Detalles Bibliográficos
Autores principales: Cook, Andrew D., Louis, Cynthia, Robinson, Matthew J., Saleh, Reem, Sleeman, Matthew A., Hamilton, John A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5134062/
https://www.ncbi.nlm.nih.gov/pubmed/27908288
http://dx.doi.org/10.1186/s13075-016-1185-9

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