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Mesenchymal stem cells/multipotent stromal cells (MSCs) are glycolytic and thus glucose is a limiting factor of in vitro models of MSC starvation

BACKGROUND: Mesenchymal stem/multipotent stromal cells (MSCs) contribute to tissue repair but are challenged during wound healing when the blood supply is disrupted, thereby limiting nutrient delivery. Survival mechanisms against ‘starvation’ include autophagy, which we previously found to enhance d...

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Detalles Bibliográficos
Autores principales: Nuschke, Austin, Rodrigues, Melanie, Wells, Albin W., Sylakowski, Kyle, Wells, Alan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5134064/
https://www.ncbi.nlm.nih.gov/pubmed/27906055
http://dx.doi.org/10.1186/s13287-016-0436-7