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Bone morphogenetic protein-2-mediated pain and inflammation in a rat model of posterolateral arthrodesis

BACKGROUND: Bone morphogenetic protein-2 (BMP-2) is a pleiotropic, secreted molecule with diverse effects. The potent ability of BMP-2 to stimulate bone growth prompted its widespread clinical use for arthrodesis (spine fusion). However, elevated post-operative pain in patients treated with BMP-2 ha...

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Detalles Bibliográficos
Autores principales:	Mitchell, Kendall, Shah, Jill P., Dalgard, Clifton L., Tsytsikova, Lyubov V., Tipton, Ashley C., Dmitriev, Anton E., Symes, Aviva J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5134101/ https://www.ncbi.nlm.nih.gov/pubmed/27905881 http://dx.doi.org/10.1186/s12868-016-0314-3

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