Laryngeal involvement with fatal outcome in progressive nodular histiocytosis: A rare case report

Progressive nodular histiocytosis (PNH) represents a very rare type of non-Langerhans cell histiocytosis. It is characterized by progressive appearance of papules and nodules without spontaneous resolution. We report a 60-year-old patient with novel clinical features in the form of extensive nodulou...

Descripción completa

Detalles Bibliográficos
Autores principales: Salunke, Aarti, Belgaumkar, Vasudha, Chavan, Ravindranath, Dobariya, Rinkesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5134168/
https://www.ncbi.nlm.nih.gov/pubmed/27990389
http://dx.doi.org/10.4103/2229-5178.193913
_version_ 1782471414743302144
author Salunke, Aarti
Belgaumkar, Vasudha
Chavan, Ravindranath
Dobariya, Rinkesh
author_facet Salunke, Aarti
Belgaumkar, Vasudha
Chavan, Ravindranath
Dobariya, Rinkesh
author_sort Salunke, Aarti
collection PubMed
description Progressive nodular histiocytosis (PNH) represents a very rare type of non-Langerhans cell histiocytosis. It is characterized by progressive appearance of papules and nodules without spontaneous resolution. We report a 60-year-old patient with novel clinical features in the form of extensive noduloulcerative lesions, ichthyotic patches, and laryngeal involvement culminating in fatal outcome prior to therapeutic intervention. Although the presenting features were baffling, histopathology and immunohistochemistry clinched the diagnosis of PNH.
format Online
Article
Text
id pubmed-5134168
institution National Center for Biotechnology Information
language English
publishDate 2016
publisher Medknow Publications & Media Pvt Ltd
record_format MEDLINE/PubMed
spelling pubmed-51341682016-12-16 Laryngeal involvement with fatal outcome in progressive nodular histiocytosis: A rare case report Salunke, Aarti Belgaumkar, Vasudha Chavan, Ravindranath Dobariya, Rinkesh Indian Dermatol Online J Case Report Progressive nodular histiocytosis (PNH) represents a very rare type of non-Langerhans cell histiocytosis. It is characterized by progressive appearance of papules and nodules without spontaneous resolution. We report a 60-year-old patient with novel clinical features in the form of extensive noduloulcerative lesions, ichthyotic patches, and laryngeal involvement culminating in fatal outcome prior to therapeutic intervention. Although the presenting features were baffling, histopathology and immunohistochemistry clinched the diagnosis of PNH. Medknow Publications & Media Pvt Ltd 2016 /pmc/articles/PMC5134168/ /pubmed/27990389 http://dx.doi.org/10.4103/2229-5178.193913 Text en Copyright: © Indian Dermatology Online Journal http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Case Report
Salunke, Aarti
Belgaumkar, Vasudha
Chavan, Ravindranath
Dobariya, Rinkesh
Laryngeal involvement with fatal outcome in progressive nodular histiocytosis: A rare case report
title Laryngeal involvement with fatal outcome in progressive nodular histiocytosis: A rare case report
title_full Laryngeal involvement with fatal outcome in progressive nodular histiocytosis: A rare case report
title_fullStr Laryngeal involvement with fatal outcome in progressive nodular histiocytosis: A rare case report
title_full_unstemmed Laryngeal involvement with fatal outcome in progressive nodular histiocytosis: A rare case report
title_short Laryngeal involvement with fatal outcome in progressive nodular histiocytosis: A rare case report
title_sort laryngeal involvement with fatal outcome in progressive nodular histiocytosis: a rare case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5134168/
https://www.ncbi.nlm.nih.gov/pubmed/27990389
http://dx.doi.org/10.4103/2229-5178.193913
work_keys_str_mv AT salunkeaarti laryngealinvolvementwithfataloutcomeinprogressivenodularhistiocytosisararecasereport
AT belgaumkarvasudha laryngealinvolvementwithfataloutcomeinprogressivenodularhistiocytosisararecasereport
AT chavanravindranath laryngealinvolvementwithfataloutcomeinprogressivenodularhistiocytosisararecasereport
AT dobariyarinkesh laryngealinvolvementwithfataloutcomeinprogressivenodularhistiocytosisararecasereport

Ejemplares similares