Inhibition of integrin β3, a binding partner of kallistatin, leads to reduced viability, invasion and proliferation in NCI-H446 cells

BACKGROUND: Kallistatin is a serine proteinase inhibitor and heparin-binding protein. It is considered an endogenous angiogenic inhibitor. In addition, multiple studies demonstrated that kallistatin directly inhibits cancer cell growth. However, the molecular mechanisms underlying these effects rema...

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Detalles Bibliográficos
Autores principales: Wang, Guoquan, Wang, Xiao, Huang, Xiaoping, Yang, Huiyong, Pang, Suqiu, Xie, Xiaolan, Zeng, Shulan, Lin, Junsheng, Diao, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5134261/
https://www.ncbi.nlm.nih.gov/pubmed/27980455
http://dx.doi.org/10.1186/s12935-016-0365-7

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