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Smoking is associated with the concurrent presence of multiple autoantibodies in rheumatoid arthritis rather than with anti-citrullinated protein antibodies per se: a multicenter cohort study

BACKGROUND: The contribution of smoking to rheumatoid arthritis (RA) is hypothesized to be mediated through formation of anti-citrullinated protein antibodies (ACPA). In RA, however, autoantibodies such as ACPA, rheumatoid factor (RF), and anti-carbamylated protein antibodies (anti-CarP) often occur...

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Detalles Bibliográficos
Autores principales: van Wesemael, Tineke J., Ajeganova, Sofia, Humphreys, Jennifer, Terao, Chikashi, Muhammad, Ammar, Symmons, Deborah P. M., MacGregor, Alex J., Hafström, Ingiäld, Trouw, Leendert A., van der Helm-van Mil, Annette H. M., Huizinga, Tom W. J., Mimori, Tsuneyo, Toes, René E. M., Matsuda, Fumihiko, Svensson, Björn, Verstappen, Suzanne M. M., van der Woude, Diane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5134292/
https://www.ncbi.nlm.nih.gov/pubmed/27906045
http://dx.doi.org/10.1186/s13075-016-1177-9