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Different effect of testosterone and oestrogen on urinary excretion of metformin via regulating OCTs and MATEs expression in the kidney of mice

The aim of this study was to investigate the effect of testosterone and oestrogen on regulating organic cation transporters (Octs) and multidrug and toxin extrusions (Mates) expression in the kidney of mice and urinary excretion of metformin. 8 week‐old male db/db mice were treated with estradiol (5...

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Detalles Bibliográficos
Autores principales: He, Rui, Ai, Ligen, Zhang, Dandan, Wan, Lili, Zheng, Taishan, Yin, Jun, Lu, Huijuan, Lu, Junxi, Lu, Fengdi, Liu, Fang, Jia, Weiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5134372/
https://www.ncbi.nlm.nih.gov/pubmed/27469532
http://dx.doi.org/10.1111/jcmm.12922