Enhanced pro‐protein convertase subtilisin/kexin type 9 expression by C‐reactive protein through p38MAPK‐HNF1α pathway in HepG2 cells

Plasma C‐reactive protein (CRP) concentration is associated positively with cardiovascular risk, including dyslipidemia. We suggested a regulating role of CRP on pro‐protein convertase subtilisin/kexin type 9 (PCSK9), a key regulator of low‐density lipoprotein (LDL) metabolism, and demonstrated the...

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Detalles Bibliográficos
Autores principales: Cui, Chuan‐Jue, Li, Sha, Zhu, Cheng‐Gang, Sun, Jing, Du, Ying, Zhang, Yan, Wu, Na‐Qiong, Guo, Yuan‐Lin, Xu, Rui‐Xia, Gao, Ying, Li, Jian‐Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5134380/
https://www.ncbi.nlm.nih.gov/pubmed/27633999
http://dx.doi.org/10.1111/jcmm.12931

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