High Temperature Requirement A1 and Fibronectin: Two Possible Players in Placental Tissue Remodelling

High temperature requirement A1 (HtrA1) is a secreted protease involved in placental development. Fibronectin (FN) is involved in important process such as wound healing, cell adhesion and spreading, growth, migration, and differentiation. The purpose of this study was to analyse the expression patt...

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Detalles Bibliográficos
Autores principales: Tossetta, G., Avellini, C., Licini, C., Giannubilo, S.R., Castellucci, M., Marzioni, D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PAGEPress Publications, Pavia, Italy 2016
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5134679/
https://www.ncbi.nlm.nih.gov/pubmed/28076935
http://dx.doi.org/10.4081/ejh.2016.2724
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author Tossetta, G.
Avellini, C.
Licini, C.
Giannubilo, S.R.
Castellucci, M.
Marzioni, D.
author_facet Tossetta, G.
Avellini, C.
Licini, C.
Giannubilo, S.R.
Castellucci, M.
Marzioni, D.
author_sort Tossetta, G.
collection PubMed
description High temperature requirement A1 (HtrA1) is a secreted protease involved in placental development. Fibronectin (FN) is involved in important process such as wound healing, cell adhesion and spreading, growth, migration, and differentiation. The purpose of this study was to analyse the expression patterns of HtrA1 in relationship to FN and to the key growth zones of placenta such as mesenchymal villi as well as cell islands and cell columns. We demonstrated that FN and HtrA1 are localized in the placental key growth zones suggesting a pivotal role in maintaining the balance among the molecules involved in the placental development and differentiation.
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spelling pubmed-51346792016-12-09 High Temperature Requirement A1 and Fibronectin: Two Possible Players in Placental Tissue Remodelling Tossetta, G. Avellini, C. Licini, C. Giannubilo, S.R. Castellucci, M. Marzioni, D. Eur J Histochem Brief Report High temperature requirement A1 (HtrA1) is a secreted protease involved in placental development. Fibronectin (FN) is involved in important process such as wound healing, cell adhesion and spreading, growth, migration, and differentiation. The purpose of this study was to analyse the expression patterns of HtrA1 in relationship to FN and to the key growth zones of placenta such as mesenchymal villi as well as cell islands and cell columns. We demonstrated that FN and HtrA1 are localized in the placental key growth zones suggesting a pivotal role in maintaining the balance among the molecules involved in the placental development and differentiation. PAGEPress Publications, Pavia, Italy 2016-11-21 /pmc/articles/PMC5134679/ /pubmed/28076935 http://dx.doi.org/10.4081/ejh.2016.2724 Text en ©Copyright G. Tossetta et al. http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Brief Report
Tossetta, G.
Avellini, C.
Licini, C.
Giannubilo, S.R.
Castellucci, M.
Marzioni, D.
High Temperature Requirement A1 and Fibronectin: Two Possible Players in Placental Tissue Remodelling
title High Temperature Requirement A1 and Fibronectin: Two Possible Players in Placental Tissue Remodelling
title_full High Temperature Requirement A1 and Fibronectin: Two Possible Players in Placental Tissue Remodelling
title_fullStr High Temperature Requirement A1 and Fibronectin: Two Possible Players in Placental Tissue Remodelling
title_full_unstemmed High Temperature Requirement A1 and Fibronectin: Two Possible Players in Placental Tissue Remodelling
title_short High Temperature Requirement A1 and Fibronectin: Two Possible Players in Placental Tissue Remodelling
title_sort high temperature requirement a1 and fibronectin: two possible players in placental tissue remodelling
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5134679/
https://www.ncbi.nlm.nih.gov/pubmed/28076935
http://dx.doi.org/10.4081/ejh.2016.2724
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