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Improved B cell development in humanized NOD‐scid IL2Rγ(null) mice transgenically expressing human stem cell factor, granulocyte‐macrophage colony‐stimulating factor and interleukin‐3

INTRODUCTION: Immunodeficient mice engrafted with human immune systems support studies of human hematopoiesis and the immune response to human‐specific pathogens. A significant limitation of these humanized mouse models is, however, a severely restricted ability of human B cells to undergo class swi...

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Detalles Bibliográficos
Autores principales:	Jangalwe, Sonal, Shultz, Leonard D., Mathew, Anuja, Brehm, Michael A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2016
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5134721/ https://www.ncbi.nlm.nih.gov/pubmed/27980777 http://dx.doi.org/10.1002/iid3.124

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