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Macrophagic control of the response to uropathogenic E. coli infection by regulation of iron retention in an IL‐6‐dependent manner

INTRODUCTION: Uropathogenic Escherichia coli (UPEC), the causative agent of over 85% of urinary tract infections (UTIs), elaborate a number of siderophores to chelate iron from the host. On the other hand, the host immune imperative is to limit the availability of iron to the bacteria. Little is kno...

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Detalles Bibliográficos
Autores principales: Owusu‐Boaitey, Nana, Bauckman, Kyle A., Zhang, Tingxuan, Mysorekar, Indira U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5134725/
https://www.ncbi.nlm.nih.gov/pubmed/27980776
http://dx.doi.org/10.1002/iid3.123